NAD+ side effects: the dose behind them, and why most prices hide it
The effects people report from NAD+ — the flushing and chest pressure during an infusion, the discomfort at an injection site — are widely described as dose- and rate-dependent. Whether that is true, and what any of it means for a particular person, is a clinical question, and this site is not the place to answer it. Ask a clinician.
There is a different question sitting underneath it that is answerable from published prices, and almost nobody asks it: if the effect depends on the dose, can you find out what dose you are buying? We read 376 NAD+ prices from 106 sellers on September 2026. For 250 of them, the answer is no.
A dose-dependent effect needs a dose
“Start low, go slow” is the standard advice for anything whose unwanted effects track the amount and the speed of delivery. It assumes the buyer knows the amount. In this market that assumption fails more often than it holds.
Prices stating a dose of any kind
126 of 376
Distinct prices stating enough to compute a milligram total
18 of 344 — 55 more were examined and refused
Prices a reader can actually see on the seller's page
335 of 376 — 41 exist only in the markup
Computed at build time from the roster read on September 2026. “States no dose” is an exact string match against the corpus’s own sentinel value, not a pattern over prose — a matcher looking for the word “mg” would score a shipping weight and a vial size as doses. The empty part of each track is the finding.
The gap between the first bar and the second is the interesting one. 126 prices state something about dose. Far fewer state something a person can turn into a number, because “a dose” in this market includes concentrations with no volume beside them, ranges, ceilings, vial sizes and titration schedules. Each of those is a real answer to “how much is in it” and none of them is a total.
Two sessions, one name, four times the load
Where doses are printed, the spread between products sharing a name is the thing worth seeing. One clinic in this roster sells two infusions side by side:
$250.00 for 250 mg, and $500.00 for 500 mg — both listed as an NAD+ infusion, both “per infusion”.
Those are honest listings and they are unusually good ones: the milligrams are printed beside the money, which is all this site ever asks of a seller. The point is what they reveal about everyone else. A reader who books “an NAD+ infusion” without checking could receive either, and the two differ by a factor of 2 — 250 mg against 500 mg, both totals these listings state themselves. If the effects people describe really do track dose and infusion rate, that is the whole question, decided by a line of small print.
Compare a second clinic in the same roster pricing the same route:
$750 for “1 session” — with no dose stated.
$750 against $500.00 looks like a price comparison. It is not one, because only one of the two says what is in the bag. This site will not divide the first figure by anything, will not estimate its milligrams, and leaves it off the cost-per-milligram board rather than guessing it onto the axis.
Why the route decides the load
The other reason a dose is hard to reason about here is that the routes are not delivering comparable quantities on comparable schedules. An infusion puts a large amount in over an hour. A subcutaneous plan spreads a much smaller amount across a month. A nasal spray is a third pattern again.
of the 376 prices in the roster
Counted from the route field, a closed enumeration decided by hand from each seller’s own printed words, in the roster read on September 2026. The scale is the roster total rather than the tallest row, so two figures on this site can be compared against each other.
109 of the 376 prices do not say which of these they are. For those, a buyer knows neither the amount nor the delivery pattern, which are the two variables the whole “start low, go slow” idea is built on.
This is also why cost per milligram is worth computing and worth reading carefully. A $700 infusion delivering 750 mg and a monthly subcutaneous plan are the same kind of number once divided, and they are still not the same experience. The board prints the route on every row for exactly that reason.
What we refuse to do with these numbers
We also refuse to estimate a missing dose. It would be easy to take a seller’s “1000 MG/ML” and multiply it by a vial size we assumed, and the resulting milligram total would be indistinguishable on the page from one a seller stated. Of the 73 distinct prices that stated a dose and could plausibly have been turned into a total, 18 were admitted and 55 were refused, each under a named rule. On the prices that survived, 13 of the milligram totals are the seller’s own and the remaining 5 are our multiplication, labelled as ours wherever they appear.
Why 55 prices that state a dose still have no milligram total
Every refusal is recorded against a named clause rather than a general “insufficient data”. The commonest is that a price states a dose per unit and never says how many units a cycle contains — a real dose and a real price that still cannot be combined. Others are floors (“from $X”), which are not a price for a specific quantity; introductory rates, which are not the standing price; prices whose cycle could not be resolved; and one where the stated cycle and the stated unit count contradict each other.
The build fails if the pool of prices that ought to be admitted and the hand-typed ruling table disagree in either direction, so a price cannot quietly appear on or disappear from the board.
250 of 376
prices stating no dose at all
18 of 344
distinct prices with a computable milligram total
109 of 376
prices naming no route
41 of 376
figures present in the markup but never shown
Does this page tell me what NAD+ side effects are?
No, deliberately. It has no clinical reviewer behind it and will not pretend to. What it establishes is that anything dose-dependent is unanswerable from 250 of the 376 prices we read, because they state no dose. Take the clinical question to a clinician.
Why not just estimate the dose from the concentration?
Because a concentration without a volume is not a quantity. “1000 MG/ML” becomes a milligram total only once you assume a vial size, and an assumed number looks exactly like a stated one on a finished page. Every milligram total on this site is either the seller’s own or our multiplication of two figures they printed, and it says which.
How do I compare two clinics if neither states a dose?
You cannot, on cost per milligram, and this site will not pretend otherwise. What you can do is ask each of them for the milligrams before booking, and then run both answers through the calculator, which does the division and carries no paid links at all.
Are these prices still current?
They were read on September 2026 and carry that date wherever they appear. A price with no verification date is wrong about half the time. This roster was read on a single day, so it can tell you exactly when — and nothing at all about how prices have moved since.